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Since 1870, the Humane Society of Missouri has been dedicated to second chances. We provide a safe and caring haven to all animals in need – large and small – that have been abused, neglected or abandoned. Our mission is to end the cycle of abuse and pet overpopulation through our rescue and investigation efforts, spay/neuter programs and educational classes. We are committed to creating lasting relationships between people and animals through our adoption and shelter pet behavior programs and by making available world-class veterinary care. The animals thank you for your support.


Formed in 2002, Helping Strays ' mission is to rescue, shelter, and rehabilitate homeless pets, find them loving homes, and promote responsible pet ownership.

Image by Karel Van der Auwera
Image by Anthony Duran

Gateway Pet Guardians (GPG) is a partner in the community, spearheading innovative and comprehensive programming with the goal of keeping pets and people together. We strive to create a community of healthy pets and empowered pet owners.


Carol House Quick Fix Pet Clinic aims to reduce pet overpopulation by providing an effective, accessible and affordable pet services. PSG is happy to support such a great organization.

Image by Markus Winkler
Image by Jeff Moore

Even Chance strives to counteract misinformation about pit bulls with factual education, communication, and resources for the general public as well as the pit bull community. We rescue temperamentally sound dogs from shelters, including dogs with medical needs and dogs rescued from organized fighting rings or other inhumane situations. We provide foster care for our rescued dogs until they are placed in forever homes.


Stray Rescue's mission is to seek out and take in those who no other organization will help or would simply euthanize because they are too expensive to heal. We rescue the abandoned, beaten, bred, fought, injured, terrified, defeated and betrayed. The minute they enter our doors, we look in their eyes and promise them ALL the second chance they deserve for health, home, commitment and love, no matter the time or cost.

Image by Margarita Kosior

Open Door Animal Sanctuary, founded in 1975, is the largest no-kill sanctuary in the greater St. Louis area and State of Missouri. We serve the community by taking in stray, abused, neglected and otherwise unwanted cats and dogs and placing them up for adoption. Each day we provide shelter, food, medical care and LOVE to an average of 350 animals. Every animal that comes to us has a home and a second chance at life.


A place of healing for both animals and people using progressive programs. The ranch sits on 20 acres and as you pull in you are greeted by the animals who call the farm home. Each animal, from the horses to donkeys, cattle to pigs, senior to differently-abled dogs, and many others are waiting to share their stories with you. These animals were rescued from some of the worst abuse, neglect and abandonment cases, yet here they are welcoming you to their home. A subsidiary of Stray Rescue STL.

Image by Filipe Dos Santos Mendes
Image by Yann Dos Santos

Hope is a non-profit corporation and their mission is one of compassion for the homeless and rehabilitation for the physically and mentally abused. Their goals are to promote spay/neuter, stop the use of gas chambers to kill our homeless pets, and to educate people on how to treat all animals with respect and dignity. They are a true RESCUE. They pull animals on their last day of life at animal control facilities and work with Animal Welfare Agencies at the City and State level regarding the abused and neglected, so that they may find a true second chance within Hope's adoption program.  


NTTSARS is a non-profit 501(c)(3), no kill, volunteer rescue that is dedicated to providing a better life for homeless, abused and neglected animals. NTTSARS is run solely by volunteers to help save animals and prepare them to become a family companion. NTTSARS is dedicated to caring for these animals in our communities through adoption, vetting, training, sanctuary, cruelty investigation and community awareness as well as food pantry and low cost services when we are able.

Image by Margarita Kosior

When PAWS Chicago was founded in 1997, more than 800 homeless cats and dogs were being killed in Chicago every week, totaling a staggering 42,561 deaths that year alone. And no one knew. PAWS Chicago was founded to end the unnecessary killing of homeless pets by informing and engaging the public and the media to help bring about change. Everything we do is inspired by our mission, values and vision.


C.A.R.E. provides rescue and adoption services to animals in need. As a no-kill shelter, we accept animals rescued by citizens and volunteers while supporting all shelters, animal control units and other rescue organizations. C.A.R.E is a family based no-kill animal rescue. They take in cats, dogs, and some farm animals.

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